Hexsel D, Zague V, Schunck M, Siega C, Camozzato FO, Oesser S. Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails. Zdzieblik D, Jendricke P, Oesser S, Gollhofer A, Knig D. The Influence of Specific Bioactive Collagen Peptides on Body Composition and Muscle Strength in Middle-Aged, Untrained Men: A Randomized Controlled Trial. Because the law does not require cosmetics to be approved by the FDA (Food and Drug Administration), topical skin care products containing collagen peptides are not regulated.
How Collagen Affects Inflammation: Collagen for Joint What is the latest research on the form of cancer Jimmy Carter has? WebThis study examined whether consuming collagen peptides (CP) before and after strenuous exercise alters markers of muscle damage, inflammation and bone turnover. Creams have the advantage of providing extra hydration, making them particularly suitable for dry, wrinkled, or aging skin, and they pose even fewer risks than the already rare potential side effects of oral supplements. Headache; Diarrhea. Clin Exp Dermatol. Collagen supplements have the potential to cause both headaches and migraines. It is made up of amino acids which build our skin, connective tissue, organs, and bones and plays a role in forming the fibroblasts (cell clusters) which allow new cells to grow and replace dead ones. 2022 Sep 2;23(1):113. doi: 10.1186/s10194-022-01478-w. Medicine (Baltimore). Many people know collagen for its role in supporting skin health and vitality. Your body makes collagen naturally, but you can also consume it through collagen supplements Looking older: fibroblast collapse and therapeutic implications. De Luca C, Mikhal'chik EV, Suprun MV, et al. Accessibility WebCollagen is so big and challenging that we cant absorb it as is when we consume it. Effect of Collagen Hydrolysate and Fish Oil on High-Sensitivity C-Reactive Protein and Glucose Homeostasis in Patients with severe Burn; a Randomized Clinical Trial. Effects of protein supplements on muscle damage, soreness and recovery of muscle function and physical performance: a systematic review. 2015;14(3):30-8. As always, if you have any concerns or Learn more about collagen vs. biotin. Clark KL, Sebastianelli W, Flechsenhar KR, et al. Please enable it to take advantage of the complete set of features! View abstract. View abstract. Protein and Sport: Alternative Sources and Strategies for Bioactive and Sustainable Sports Nutrition. J Sci Food Agric. View abstract. Additional research is necessary to fully prove the effects that collagen has on promoting strong bones, however. 2012;7:267-273. View abstract. J Cosmet Dermatol 2019;18(6):1693-1699. However, such claims do not yet have scientific evidence to support them. government site. The participants study took 15 grams (g) of collagen or a placebo pill per day. Using a double-blind, independent group's design, 24 recreationally active males consumed either 20 g day-1 of CP or a placebo control (CON) for 7 days before and 2 days after performing 150 drop jumps. Kim DU, Chung HC, Choi J, Sakai Y, Lee BY. Moskowitz RW. Conformational Changes in Proteins Caused by High-Pressure Homogenization Promote Nanoparticle Formation in Natural Bone Aqueous Suspension. Trc T, Bohmov J. Efficacy and tolerance of enzymatic hydrolysed collagen (EHC) vs. glucosamine sulphate (GS) in the treatment of knee osteoarthritis (KOA). Dietary supplements do not improve bone morphology or mechanical properties in young female C57BL/6 mice. Kim HY, Lee JD, Lee YH, Seo SW, Lee HS, Kim S, Kim KB. This site needs JavaScript to work properly. IMPORTANT NOTE: Looking for fruits that help to relieve constipation? de Miranda RB, Weimer P, Rossi RC. Reumatismo. Accessibility Be the first to hear about exclusive offers and latest arrivals. Of those side effects, there has been a recurring theme among many collagen users asking: can taking collagen cause headaches? Epub 2013 Dec 24. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). The .gov means its official. 2018;10(1). Burns. Schwartz SR, Park J. Ingestion of BioCell Collagen, a novel hydrolyzed chicken sternal cartilage extract; enhanced blood microcirculation and reduced facial aging signs. National Library of Medicine Webcan collagen supplements cause headaches? One study found that Miyanaga M, Uchiyama T, Motoyama A, Ochiai N, Ueda O, Ogo M. Oral Supplementation of Collagen Peptides Improves Skin Hydration by Increasing the Natural Moisturizing Factor Content in the Stratum Corneum: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Sci Rep. 2022 Jun 13;12(1):9804. doi: 10.1038/s41598-022-14068-2. Koizumi S, Inoue N, Sugihara F, Igase M. Effects of collagen hydrolysates on human brain structure and cognitive function: A pilot clinical study. 2023 Feb;13(2):523-534. doi: 10.1007/s13555-022-00859-y. Choi SY, Kim WG, Ko EJ, et al. Is the ketogenic diet right for autoimmune conditions? Bauza E, Oberto G, Berghi A, Dal CF, Domloge N. Collagen-like peptide exhibits a remarkable antiwrinkle effect on the skin when topically applied: in vivo study. Int J Environ Res Public Health 2021;18(9):4837. Nutrients 2018;10(10). HIGH CHOLESTEROL on Keto Diet (My 4-Year High Fat Diet Results!) Collagen and biotin may both help promote skin and hair health, but each has different pros and cons. The less your body has to work to break down the collagen when you consume it, the less likely you are to get a stomach ache or other unwanted side effects. What we can do however, is hydrolyze the collagen, which means its broken down into much smaller sized pieces ( peptides) by water, making it usable by your body. Prowting JL, Bemben D, Black CD, Day EA, Campbell JA. 2008;24(5):1485-96. MeSH J Neuroimmune Pharmacol. Lis DM, Jordan M, Lipuma T, Smith T, Schaal K, Baar K. Collagen and Vitamin C Supplementation Increases Lower Limb Rate of Force Development. WebGlutamate is implicated in cortical spreading depression, trigeminovascular activation, and central sensitization. A calcium-collagen chelate dietary supplement attenuates bone loss in postmenopausal women with osteopenia: a randomized controlled trial. Effects of hydrolyzed collagen supplementation on skin aging: a systematic review and meta-analysis. However, these claims do not have backing by scientific research. National Library of Medicine Camilion JV, Khanna S, Anasseri S, Laney C, Mayrovitz HN. Our team thoroughly researches and evaluates the recommendations we make on our site. Unauthorized use of these marks is strictly prohibited. Other potential side effects of collagen peptides in individuals with sensitivities or for those using poor quality collagen products include the following: If you are sensitive to the free glutamic acid found in collagen protein, you may experience mild headaches or have difficulty sleeping.
Health Benefits of Collagen: Pros and Cons, Nutrition, and More A wide range of dietary supplements is offered to improve skin health. Therapeutic role of melatonin in migraine prophylaxis: A systematic review. View abstract. Benefits of sunlight: a bright spot for human health. Federal government websites often end in .gov or .mil.
Peptides By following these tips, you can help ensure safe use of collagen peptides powder and minimize the risk of side effects or health issues. Rheumatoid arthritis, lupus, dermatomyositis and scleroderma are autoimmune, connective tissue diseases known to damage collagen. The site is secure. Inoue N, Sugihara F, Wang X. Ingestion of bioactive collagen hydrolysates enhance facial skin moisture and elasticity and reduce facial ageing signs in a randomised double-blind placebo-controlled clinical study. As with any supplement, collagen supplements do have some potential side effects, especially when taken in excess. 5. Effects of collagen peptides on recovery following eccentric exercise in resistance-trained males-A pilot study. A 2016 animal study also found that collagen hydrolysate (also called collagen peptides) reduced fat cell size and weight gain in rats. Mar Drugs. Mar Drugs. Wauquier F, Boutin-Wittrant L, Bouvret E, Le Faouder J, Roux V, Macian N, Pickering G, Wittrant Y. Nutrients. Conclusions and Relevance: Preliminary results are promising for the short and long-term use of oral collagen supplements for wound healing and skin aging. Also, in many cases, the collagen is hydrolyzed. If you buy through links on this page, we may earn a small commission Heres our process. We include products we think are useful for our readers. Some collage supplements do source from these animals, so when taking them, youre likely to have an allergic reaction of some kind., The question of whether collagen can cause headaches or not is somewhat subjective, but the short answer is yes.
Collagen In general, the side effects of collagen supplements are mild and can include: Otherwise, in most adults, taking collagen supplements should not pose any significant health risks. Role of collagen hydrolysate in bone and joint disease. Praet SFE, Purdam CR, Welvaert M, et al. For most people, taking collagen should not have any major effects or health consequences. Lim, S. H., Sun, Y., Thiruvallur Madanagopal, T., Rosa, V., & Kang, L. (2018). Oxid Med Cell Longev.
Collagen Ranchordas MK, Rogerson D, Soltani H, Costello JT. Collagen is the most abundant protein in the human body. View abstract. This Migraine pain-relay centers, including the trigeminal ganglion, trigeminal nucleus caudalis, and thalamus, contain glutamate-positive neurons, and glutamate activates the trigeminal nucleus caudalis. Collagen is a protein that promotes skin elasticity. View abstract. Still, the only real risk with collagen is knowing the source, quality, and reliability of the supplement company., It is important to get to know the company you are buying a supplement from and to ensure that they are transparent about all of their ingredients and product sourcing., If the company is not transparent, and you have no idea what is in the supplement, there is a higher chance the collagen can cause headaches and other issues., Beyond the product itself and ingredients, dosage can also impact how safe it is to use collagen as a daily supplement., As with anything, it is possible to take too much and have an adverse reaction. 2010;65(3):253-7. Information from this source is evidence-based and objective, and without commercial influence. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Prokopov A, Pavlackov J, Mokrejs P, Gl R. Collagen Hydrolysate Prepared from Chicken By-Product as a Functional Polymer in Cosmetic Formulation. WebCollagen is a protein responsible for healthy joints and skin elasticity, or stretchiness. Sibilla S, Godfrey M, Brewer S, Budh-Raja A, Genovese L. An overview of the beneficial effects of hydrolysed collagen as a nutraceutical on skin properties: Scientific background and clinical studies. View abstract. 2017 Dec 14;12(12):CD009789. J Cosmet Dermatol. Ex vivo experiments demonstrated that collagen peptides induce collagen as well as glycosaminoglycan production, offering a mechanistic explanation for the observed clinical effects. Unable to load your collection due to an error, Unable to load your delegates due to an error. Zehra A, Burns J, Liu CK, et al. View abstract. Would you like email updates of new search results? Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women-A Randomized Controlled Study. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction. Human skin explants were used to study extracellular matrix components in the presence of collagen peptides ex vivo. Something that should be recognized about collagen as a supplement is that it is natural. Nutrients. However, more research is necessary to prove the effects of collagen in supporting heart health. pii: E76. Effect of dietary supplementation with collagen hydrolysates on bone metabolism of postmenopausal women with low mineral density. Maia Campos PMBG, Franco RSB, Kakuda L, Cadioli GF, Costa GMD, Bouvret E. Oral Supplementation with Hydrolyzed Fish Cartilage Improves the Morphological and Structural Characteristics of the Skin: A Double-Blind, Placebo-Controlled Clinical Study. Then, we recommend you evaluate the supplement itself along with the dosage you have been using., Not all collagen supplements are created equal and whether collagen can cause headaches may have more to do with the type of collagen you use and its bioavailability to you., When looking at the quality of a collagen supplement, first and foremost check to see if the company can back up their claims., If a company is making any kind of result claims regarding collagens ability to help resolve issues (especially medical issues) then they need to have resources, case studies, and other research to back up these claims., Since the FDA does not regulate collagen supplements as closely as they should, a lot of this is left up to the consumer to identify and sift through. ANSWER: Collagen and biotin supplements appear to be getting attention in the media for promoting healthy aging, along with joint and bone health.
Collagen Peptides: What They Can and Can't Do for Real - Greatist Type 1: This is one of the most abundant types present in the human body and helps support healthy skin. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. 2020;20(1):12-17.View abstract.
Collagen Unfortunately, our bodies produce about 1% less collagen 1 with each passing year, and we're
Can Bruyre O, Zegels B, Leonori L, et al. 2018 Mar;78(4):411-437. doi: 10.1007/s40265-018-0865-y. 2019;17(3). Oral Intake of Enzymatically Decomposed AP Collagen Peptides Improves Skin Moisture and Ceramide and Natural Moisturizing Factor Contents in the Stratum Corneum. Int J Mol Sci. There is some evidence to suggest that collagen supplements can help with restoring or preventing the deterioration of the cartilage in the joints. Can help clear breakouts. "The riskiest side effects of any treatment are usually allergic 2023 Copyright Derm Collective. 2000;30(2):87-99. Most collagen supplements go through the process of hydrolyzation. Main benefits: Provides moisture to the skin and scalp, strengthens the hair follicle, accelerates healing, and nourishes the hair bulb. However, it is possible to have too much of a good thing., If calcium is the cause of your collagen-related headache problems, then a simple change in collagen supplement dosage may be in order to reduce the likelihood that your collagen can cause headaches., If you are worried about or already are experiencing headaches from your collagen supplements then it is best to consult a medical professional. Kynurenines and PACAP in Migraine: Medicinal Chemistry and Pathogenetic Aspects. anti-aging; collagen peptides; fragmentation; glycosaminoglycan; hyaluronic acid; reflectance confocal microscopy. Effect of Calcium and Vitamin D Supplementation With and Without Collagen Peptides on Volumetric and Areal Bone Mineral Density, Bone Geometry and Bone Turnover in Postmenopausal Women With Osteopenia. Efficacy and Safety of Topical or Oral Hydrolyzed Collagen in Women with Dermatoporosis: A Randomized, Double-Blind, Factorial Design Study.
SkinnyFit Super Youth Side Effects Maia Campos PMBG, Melo MO, Siqueira Csar FC. WebAutoimmune diseases (your bodys immune system attacks its own tissue) can damage collagen. These include: Collagen peptide supplements can offer a range of benefits from improved skin health to a reduction in joint pain and stronger hair and nails. 2020;111(3):708-718. Knight, J., Jiang, J., Assimos, D. G., & Holmes, R. P. (2006). Appl Physiol Nutr Metab. Always take your collagen peptide supplements as instructed by a healthcare professional or as directed on the label of a product. ANSWER: Collagen and biotin supplements appear to be getting attention in the media for promoting healthy aging, along with joint and bone health. Lin P, Alexander RA, Liang CH, et al. Collagen supplements are available in the form of tablets, capsules, and powders. The ingredients list is going to be very telling when looking at any supplement., Consider if there are several additives or unnatural ingredients. However, some vegan and vegetarian collagen options are available. Keywords: A pilot study for the detection of cyclic prolyl-hydroxyproline (Pro-Hyp) in human blood after ingestion of collagen hydrolysate. 2015 The Authors. Jendricke P, Kohl J, Centner C, Gollhofer A, Knig D. Influence of specific collagen peptides and concurrent training on cardiometabolic parameters and performance indices in women: A randomized controlled trial. MNT is the registered trade mark of Healthline Media. 2023 Jan;13(1):e2820. Curr Med Res Opin. It is advisable to cautiously watch your collagen intake as excessive consumption often leads to some mild reactions. The answer is yes., a study published in the Journal of the American Medical Association, found that people who took collagen-based Unauthorized use of these marks is strictly prohibited. There is some evidence to suggest that using collagen supplements may help increase muscle mass. The role of glutamate and its receptors in migraine. View abstract. Pressure ulcer healing with a concentrated, fortified, collagen protein hydrolysate supplement: a randomized controlled trial. Yamamoto S, Deguchi K, Onuma M, Numata N, Sakai Y. Absorption and Urinary Excretion of Peptides after Collagen Tripeptide Ingestion in Humans. Would you like email updates of new search results? View abstract. Potential Cosmetic Active Ingredients Derived from Marine By-Products. Although certain foods, such as bone broth, contain collagen, people who want wrinkle-free skin or other health benefits often look to supplements to increase their collagen intake. One amino acid in particular, glutamic acid We currently have no information for COLLAGEN PEPTIDES overview. Effects of Collagen Peptides on Recovery Following Eccentric Exercise in Resistance-Trained Males-A Pilot Study. and transmitted securely. Oliviero F, Ramonda R, Hoxha A, et al. Benito-Ruiz P, Camacho-Zambrano MM, Carrillo-Arcentales JN, et al. Dizziness. Biol Pharm Bull. J Agric Food Chem. Type 2: This is present primarily in cartilage and can help promote joint health. This means that the manufacturer has broken the collagen in the supplements down into peptides, making it easier for the body to absorb and use. Prowting JL, Bemben D, Black CD, Day EA, Campbell JA. Nutrients. Hakuta A, Yamaguchi Y, Okawa T, Yamamoto S, Sakai Y, Aihara M. Anti-inflammatory effect of collagen tripeptide in atopic dermatitis. One thing that you can look for is a medical grade collagen supplement like ProT Gold., It is still a possibility that you may experience some side effects with any collagen supplement. 2004;26(3-4):105-11. Collagen is a type of structural protein in the body. The https:// ensures that you are connecting to the Collagen loss with age can cause increased tooth sensitivity and decreased tooth strength.
Can Collagen Cause People can consume collagen supplements they purchase from a number of online and local stores, and they can usually find a type that matches their specific dietary needs.
Can Collagen Supplements Cause Headaches - TheFitnessManual This site needs JavaScript to work properly. pii: E1356. Speak with a, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Osteoarthritis. 2015 Dec;14(4):291-301. Mohammed A, He S. A Double-Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy of a Hydrolyzed Chicken Collagen Type II Supplement in Alleviating Joint Discomfort. The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. HHS Vulnerability Disclosure. Benefits of Circulating Human Metabolites from Fish Cartilage Hydrolysate on Primary Human Dermal Fibroblasts, an Ex Vivo Clinical Investigation for Skin Health Applications. Collagen is the most important structural protein in the body, critical to skin firmness, elasticity, and an overall youthful appearance. Guerrero-Toro C, Koroleva K, Ermakova E, Gafurov O, Abushik P, Tavi P, Sitdikova G, Giniatullin R. Int J Mol Sci. View abstract. Cureus. The question that often arises in the minds of people before consuming it is, Can collagen cause diarrhea? The answer to this 2019;12(1):50. Biosci Rep. 2018 Dec 14;38(6):BSR20181347. Int J Food Sci Nutr. Glutamate receptor-subtype antagonists are effective in preclinical models of migraine, and in the clinic. As with any supplement, collagen supplements do have some potential side effects, especially when taken in excess. There were no statistically significant effects for the other dependent variables (P > 0.05). sharing sensitive information, make sure youre on a federal As well, since the FDA considers collagen a dietary supplement, the safety and effectiveness of collagen peptide supplements are also unregulated. National Library of Medicine 2019;29(5):461-465. Integr Med (Encinitas). eCollection 2022 Aug. 2009;60 Suppl 2:99-113. When applied topically or ingested, products containing collagen peptides signal to your body that it needs to produce more collagen. Updated February 27, 2014. 2022 Jan 28;23(3):1529. doi: 10.3390/ijms23031529. PMC Muscle soreness was not significantly different in CP and CON (P = 0.071) but a large effect size was evident at 48 h post-exercise, indicative of lower soreness in the CP group (90.42 45.33 mm vs. CON 125.67 36.50 mm; ES = 2.64). View abstract. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). doi: 10.1002/brb3.2820. Taking collagen peptides by mouth might slightly relieve pain and improve joint function in people with. 2015;18(12):1340-8. Biosci Biotechnol Biochem. Urinary Metabolomics in Young Soccer Players after Winter Training Season. Side effects vary depending on which type of collagen supplement you take, but they are generally minor overall. Treatment with marine collagen peptides modulates glucose and lipid metabolism in Chinese patients with type 2 diabetes mellitus. Evans M, Lewis ED, Zakaria N, Pelipyagina T, Guthrie N. A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. Maturitas. View abstract. Therapeutic potential of novel glutamate receptor antagonists in migraine. Are they safe, and do they work? View abstract. Does eating these foods increase levels of collagen in the body? Expert Opin Investig Drugs. Collagen peptide supplements can however lead to dermatological, digestive side, and other side effects, particularly in products with poorly sourced ingredients. Oikawa SY, Kamal MJ, Webb EK, McGlory C, Baker SK, Phillips SM. Collagen formula with Djulis for improvement of skin hydration, brightness, texture, crow's feet, and collagen content: A double-blind, randomized, placebo-controlled trial. Allergic Reaction. View abstract. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Two placebo-controlled clinical trials were run to assess the effect of a daily oral supplementation with collagen peptides on skin hydration by corneometry, on collagen density by high-resolution ultrasound and on collagen fragmentation by reflectance confocal microscopy. Ito N, Seki S, Ueda F. Effects of Composite Supplement Containing Collagen Peptide and Ornithine on Skin Conditions and Plasma IGF-1 Levels-A Randomized, Double-Blind, Placebo-Controlled Trial.
Collagen COLLAGEN TYPE II (NATIVE Collagen Peptides Can poor sleep impact your weight loss goals?
Mayo Clinic Q and A: Collagen and biotin supplements ProT Powder Collagen Protein - 32 Servings. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. The researchers found that the women taking the calcium and the collagen had lower levels of a protein responsible for breaking down bones in their blood.
Liquid collagen: Benefits and risks for hair, skin, and more In spite of this, the FDA does monitor supplements and take legal action against any which have been proven to make false claims or which pose safety concerns. Effect of the novel low molecular weight hydrolyzed chicken sternal cartilage extract, BioCell Collagen, on improving osteoarthritis-related symptoms: a randomized, double-blind, placebo-controlled trial. Nutrients. Lpez-Martnez MI, Miguel M, Garcs-Rimn M. Front Nutr.
Marine Collagen Front Nutr. View abstract.
COLLAGEN TYPE II (NATIVE 2015;8:29-42. 4 Best Ones and Alternatives, Probiotics for Acne: Do They Work, How to Use Them and More, Try a preventative approach. So as you see, collagen can cause headaches and other issues in some people. A person should choose the supplement that best supports their goals when picking a collagen type. Apart from fatigue, this might lead to headaches and feelings of nervousness and irritability.
Collagen In this study, the women took either a collagen supplement or placebo for 8 weeks. Recent Advances in Pharmacotherapy for Migraine Prevention: From Pathophysiology to New Drugs. Health Canada. 2011;35(3):341-8. View abstract. Clin Interv Aging. Collagen is concentrated in bones, ligaments, tendons, skin, blood Whey protein but not collagen peptides stimulate acute and longer-term muscle protein synthesis with and without resistance exercise in healthy older women: a randomized controlled trial. Arch Acad Emerg Med 2021;9(1):e50. The effects of beetroot juice supplementation on indices of muscle damage following eccentric exercise.
Collagen supplements This is typically due to Theres currently 80 approved peptide drugs worldwide. Drugs. Learn more. Although some experts believe that peptide skin creams or moisturizers are not able to be absorbed fully via the skin, instead recommending oral supplements, some research has nonetheless shown them to have positive effects on skin health. Shigemura Y, Iwasaki Y, Tateno M, et al. There are several potential health benefits that collagen supplements offer. Sugihara F, Inoue N, Venkateswarathirukumara S. Ingestion of bioactive collagen hydrolysates enhanced pressure ulcer healing in a randomized double-blind placebo-controlled clinical study. 2014;39(8):874-80. Scientists describe collagenous colitis as a type of microscopic colitis because the inflammation it causes is only noticeable under a microscope. The reasons why headaches are a potential side effect of collagen are variable and not necessarily conclusive, as more research is needed on this topic., However, one common trend we found in our research for this article is that the type of collagen and quality of the supplement itself contributes a lot to the potential for side effects like headaches., It has been considered that collagen may cause headaches for some users because it can raise your calcium levels. View abstract. Many people take collagen supplements to add more collagen to their diet.
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